NEET Biology · Genetics and Evolution

Human genome project and DNA fingerprinting

Taught in NCERT Class 12 Biology, Chapter 5: Molecular Basis of Inheritance.

3 verified questions: Easy 0 · Medium 3 · NEET level 0

Sample questions

Sample 1Medium

An autoradiogram of DNA fingerprints has four lanes, each with bands numbered from the well downwards. The crime-scene sample has bands at positions 2, 5, 7 and 9. Suspect S1 has bands at 1, 5, 8 and 9; suspect S2 at 2, 5, 7 and 9; and suspect S3 at 2, 4, 7 and 10. The probe used binds a VNTR. Which conclusion is correct?

  1. A

    S1 matches, because it shares the most bands with the sample

  2. B

    S2 matches, because the VNTR band pattern is identical and VNTR copy number varies between individuals

  3. C

    S3 matches, because it shares bands 2 and 7

  4. D

    None can be identified, because VNTRs are the same in all humans

Show the answer
The answer is B.

A VNTR is a minisatellite whose copy number varies from person to person, so the size and pattern of bands differ between individuals. Only S2 shows exactly the same pattern as the crime-scene sample.

  • A.

    S1 shares only bands 5 and 9; a match needs every band to agree.

  • C.

    Sharing two bands is not a match; bands 4 and 10 do not appear in the sample.

  • D.

    VNTR copy number differs between individuals, which is why fingerprints differ.

NCERT: Class 12 Biology, Chapter 5, 5.10

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