NEET Biology · Biology and Human Welfare

Cancer, HIV and AIDS

Taught in NCERT Class 12 Biology, Chapter 7: Human Health and Disease.

3 verified questions: Easy 0 · Medium 3 · NEET level 0

Sample questions

Sample 1Medium

A diagram of HIV replication shows the virus entering a macrophage. Arrow 1 shows the viral RNA being copied into viral DNA by enzyme X. Arrow 2 shows the viral DNA entering the host DNA, after which the cell keeps producing viruses. New viruses then attack cells Y, whose numbers fall progressively. Which identification is correct?

  1. A

    X is RNA polymerase; Y are B-lymphocytes

  2. B

    X is DNA ligase; Y are macrophages only

  3. C

    X is reverse transcriptase; Y are red blood cells

  4. D

    X is reverse transcriptase; Y are helper T-lymphocytes

Show the answer
The answer is D.

After entering a macrophage, HIV's RNA genome is copied into viral DNA by reverse transcriptase and incorporated into host DNA, so the macrophage keeps producing virus. HIV then enters helper T-lymphocytes, whose number progressively decreases.

  • A.

    Viral DNA is made from RNA by reverse transcriptase, and HIV mainly attacks helper T-cells.

  • B.

    Ligase joins DNA fragments; the progressively falling cells are helper T-lymphocytes.

  • C.

    HIV attacks helper T-lymphocytes, not red blood cells.

NCERT: Class 12 Biology, Chapter 7, 7.3

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